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Liver Transplant  (Expert Forum)
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HBsAb become positive ?
Answered by
Thomas D Schiano, MD - Internal Medicine, Gastroenterology, Liver Transplantation, Hepatology
The Mount Sinai Medical Center New York - NY
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Questions posted in the Liver Transplant . Forum are answered by medical professionals from The Mount Sinai Medical Center.

HBsAb become positive ?

by khmerupgrade, Oct 04, 2009 09:45PM
Hello,
I was infected HBV twice in early 2004 and late 2005.

1) In January 2004
Symptoms: vomit, yellow skin, abdomen pain, very tired.

2) In December 2005:

1st Blood test:
-  HBsAg = (+)
- SGPT = 264 UI/L
- SGOT = 171 UI/L

I was adviced to take lamivudine 100mg/day regularly. Blood test result is as followed:

2nd  Blood test:
- SGOT = 24 UI/l
- SGPT = 10 UI/l
- Total bilirubine = 42,2 µmol/l  (N: <17,1)
- Conjugated bilirubine = 6,6 µmol/l  (N: <3,4)
- Free bilirubine = 35,6 µmol/l  (N: <13,7)
- HBsAg = (-)
- HBsAb = (+)   ;   40UI/l

Could you please confirm me the following?
1- Am I fully recovered from Hepatitis B Virus?
2- Shall I continue taking Lamivudine 100mg/day?
3- Can I drink alcohol for sometimes? (At  the party...etc)
4- Is it possible that HBsAb (+) become (-)?
5- How about the upgrade level of Bilirubine?

Best regards,

THO

by Thomas D Schiano, MD, Oct 05, 2009 11:07AM
you may have cleared the HBV spontaneously, which occurs actually in the majority of patients.  if the HBSAg is (-) then lamivudine is no longer necessary.  You should check your HBV-DNA level.  once the surface Ab becomes (+) it shouldn't become (-).  i see no problem with having a drink now and then, but never to excess.
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