Sometimes I read research briefs and think - 'well, duh! I could have told you that." - and such was the case this morning when I was reading about a presentation at the CMSC conference last week that reported people with MS vision related problems stumble more often in low-light situations than people without MS related vision problems. I was busy shaking my head at that one, and am glad I went back and read further because there really was useful news in this one.
Here is the link and the text - it might be very useful for many of you with vision difficulties -
http://www.medpagetoday.com/MeetingCoverage/CMSC-ACTRIMS/33096
"SAN DIEGO -- Vision loss, especially in low light, may contribute to problems with walking in multiple sclerosis (MS) patients, a researcher said here.
Lower visual acuity in low-contrast situations among MS patients was significantly associated with poorer performance on a gait test in a controlled trial, said Rachel Tripoli, a medical student at Florida State University in Tallahassee, Fla.
Moreover, many of the MS patients showed improvements when they wore contrast-enhancing yellow lenses, she said -- a simple and practical solution to a problem that diminishes quality of life and can cause physical injury.
Tripoli reported the findings at the joint meeting of the Consortium of Multiple Sclerosis Centers and the Americas Committee for Treatment and Research in Multiple Sclerosis.
Previous studies had indicated that reduced vision in low light was common in MS with or without overt optical neuropathy, Tripoli said.
She and colleagues recruited 22 MS patients and 22 age-matched healthy controls for their study, in which participants underwent visual and gait testing under a variety of lighting conditions.
The vision testing involved low-contrast Sloan charts, which display letters that appear increasingly faded as one reads down.
Participants also underwent optic coherence tomography scans to evaluate optic nerve morphology.
Finally, walking ability was measured on a "gait pad," a 22-foot carpet embedded with sensors that capture footfall pressure and duration, as well as gait speed and total time to traverse the pad. The data were used to calculate a functional ambulation performance (FAP) score.
Walking was evaluated under low light (less than 4 candelas) and four brightly lit (more than 80 candelas) conditions. Participants were tested four times under each lighting condition -- with and without obstacles (cones placed on the pad) and with and without contrast-enhancing yellow lenses.
The optic coherence tomography testing showed that, as expected, the MS patients had significantly decreased optic nerve thickness relative to controls, Tripoli said.
Sloan chart scores also were lower in the MS patients than in controls, she reported.
Under three different contrast conditions, MS patients were able to read about five fewer letters than controls.
On the gait tests, MS patients' FAP scores were negatively associated with EDSS disability scores, indicating that increased disability was correlated with poorer walking performance.
Differences in gait measurements in MS patients versus controls were apparent only under low light. In bright light, no significant deficiency for patients was apparent, Tripoli said.
With obstacles, the mean FAP score for patients was about 75, compared with more than 90 in controls. The difference in the obstacle-free test was smaller, about 10 points, but still significant, Tripoli said.
Use of yellow lenses improved FAP scores in patients to the point that they no longer differed significantly from controls, both with and without obstacles.
She said it was reasonable to conclude that the lenses "increase obstacle discrimination" and could be useful for injury prevention."