Hi, thanks for the answer.
So, it's possible that higher immune system could kill parasites, bacteria or candida and bad toxins increase my anxiety...
I have tried to find information of picolinic acid but I haven't found much about side effects.
It's really impossible to say. As you say, that's a low dose of zinc, well within limits, and probably not enough to leach out other nutrients to a noticeable degree. But zinc can be stimulating in small ways -- it ups immune system activity and it also can affect testosterone levels, usually in a beneficial way but I suppose a very sensitive person could notice. You also could be sensitive to the picolinic acid. With supplements, it's a process of experimentation, and by stopping this one you apparently solved the problem, which is the good thing about natural remedies -- they're almost always really easy to stop taking if there are adverse events.