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Unprotected anal - Elisa tests 4 Generation at 8 weeks

Hi!

79 days ago I had a sexual intercourse -unprotected anal sex- with a 17 years old guy unkown status, I think he is promiscous. It just was for 3 or less minutes but he came inside. I tried to remove his cum but perhaps it didn´t work.

At the 8 weeks I got a Elisa Test 4 Generation HIV1 - HIV2 & P24 Antigen and fortunately it came Non Reactive.

I Know that only at 3 months is a conclusive Test. But I have 3 Questions cause im too worried!

Questions:

1. After read a lots of questions and responses in this forum and others forums I have this conclusion: The seroconversion´s averge is at 28 days and the 93% of the people will be Reactive at 6 - 8 weeks. It is true?

2. For me how accurate was the Elisa 4 Generation that I got at 8 weeks.

3. For me which is the probability of being infected knowing that I got a non reactive elisa test 4 generation at 8 weeks.

Many many thanks for your time & help

Juan.



Best Answer
Avatar universal
Okay and now i think youre at a point where you need to apply gradations to things or at least understand that there are variances in personal judgement amongst people but not in the overall science. To start youre dealing with experts of differing opinions and i have been in your position, so ill just convey my judgement and then you should consider your own.

You obviously know you have a possible risk and you know youve been tested but it is not 100% conclusive. Now the doctors on this site at least on the experts forum are epedemiologist, which means they're dealing with their understanding of the probability of acquiring a disease and generally conduct studies at the aggregate level and the forum by dr. James on the body is dealing with his scientific perception of acquisition based on his understanding as an immunologist. Now, based on overall data the not doctors on this site nor anyone anywhere could be able to garuntee that you now know you are at no risk at all. But based on the knowledge of the information the doctors on this site have stated: 1. A result at eight weeks is extremely indicative to the likelihood of your acquisition, and i will not repeat their percentages cause your obviously aware of there understanding 2. Your risk for this singular act is considered to be around one percent at most by the cdc, the quotes from the doctors on this site and the body too, as you had a single high risk exposure and most people acquire hiv through repeated exposure 3. Most people actually do not have hiv and if you go to the cdc site on cases youll realize that even most gay men do not, especially people under the age of 18.  Now dr James on the body is an immunolist meaning he is dealing with the possibility that you could have a disease based on the functionality of your immune system. If youll look it up, his advice is all very informed and very conservative, considering he is an immunologist he rarely discounts the possibility of hiv acquisition. He repeats over and over in his analysis that if you are even remotely concerned over a risk even for things that this site sees no reason to test for, like oral receptive or insertive, or even sometimes concerns over a cut that isnt even open, he nearly always suggests testing. This difference is predominantly based on his perspective, which is that even a one in a million chance is a chance so get tested. The doctors on this site recomend testing annually for sexually active people but do not tend to be as ardent as the body's expert. This is simply based on differing perspectives.

So what do you know based on your lamens knowledge that youve acquired from experts. Dr. James on the body, the experts on this site and the cdc would all agree that it is not likely you acquired hiv from a single act and the stats you have on it are around one percent. We also know from demographic analysis that although gay men are disproportionately affected by hiv, most gay men do not have hiv. When you combine this with a strong likelihood your test further adds to the previously known likelihood that you do not often get hiv from the single act, you would have to think that you are overreacting by constantly searching for an answer you will not get until 3 months post exposure.

This means that as a logical person you could have started by knowing that the act was a big mistake, and is one you should not repeat again. Following understanding this you should also be aware that the mistake still does not have a very high likelihood of having the unfortunate effect your concerned with based on scientific studies regarding acquiring the disease. This would be further supported by your test, which is not 100% but is considered a very good indicator by the experts. Now you have to make a decision, are you going to allow this remote chance ruin your life for the next four weeks and is that logical? If you combine the percentages you have a percentage of a percentage of a chance of getting hiv from this act combined with the results you have and the fact that even most gay men dont have hiv. Could you still have it? Possibly but alot of other things could also happen and many of them like your hiv likelihood at this point are very very unlikely. So stop looking for the definative answer that can not be provided! You made a mistake and it is very likely it did not come back to haunt you THIS TIME, but you can not be sure until four weeks. So focus on your life again and consider the test in another four weeks which will be three months but stop obsessing cause you likely do not have it based on any logical persons opinion. I mean imagine if you did this about everything in your life, like walking across the street, driving places, eating food or etc because their is a percentage of a percentage you may be adversely affected. I say this not to trivialize what you did, as im sure you know it is the most likely way to get the disease but at this point it is obvious you understand it was a bad move. Yet still as long as you do not repeat it and get tested in four weeks it seems like this move will very likely not have its most unfortunate result!
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Avatar universal
I got an Elisa 4 generation Test at 80 days after exposure & fortunately it came Negative!!!

It seems like an Elisa 4 generation that i took at 8 weeks was 100% reliable!

I want to thank you all guys and please always use condom, always!

Thanks!!!!!
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Avatar universal
3 months is conclusive now move on.
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Avatar universal
The doctors do admit that it is not 100% conclusive but do also say that this is because the CDC needs to be a hundred percent correct. I will not sit here and act as if i know as much about this particular topic or any regarding hiv as either teak or the doctors on this site or the cdc. But what i can say to you is that i too have been extremely paranoid and that from the limited amount of info ive seen on this site that both of its expert forums US/international do state that they believe that a very high majority of cases would be dedected by this time and if you just do a quick scan of the random post on their forums you will find their opinions on the topic. Obviously the cdc and this sites moderater state that this is not 100% but considering the entirety of what you know you seem to be acting on irrational fear. For one why would you ask teak the question about test dedection, if the professional epedemiologists on this site state a particularly high percentage of dedection by four weeks and then by eight weeks? And again most people do not convert after a single act and then there is the fact that most people even gay men do not have hiv. I will simply conclude by saying from what ive seen here that it is seen as a very very good indication for you and your irrational fear here is a bit excessive because it is still not very likely that you have hiv judging on what ive read!

Id like to further note in response to my prior post i did not say whether or not you needed  further testing, I simply stated percentages conveyed by this sites experts on their forum. If you still desire to get tested because it is not considered to be conclusive at this point go right and head and for that matter why not? But if the doctors state that they believe that the tests at a particular time detects a particular percentage of people why do you still feel the need to continue to consult people over this redundant topic? You can scan through their forum and it would likely take you less than an hour to find definative answers regarding testing times and percentages even when the act is as high risk as yours. Needless to say i think it would be revealing to you regarding how conclusive test times and how risky a single act even as high risk as yours is. Finally you will obviously have to wait further in order to get your final results but consider the information while waiting and consider how you are acting and letting some unlikely event irrationally affect your behavior.
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Avatar universal
So, is usualy after a 8 weeks Negative Elisa 4 Generation Result change to Reactive at the 12 weeks?    or    It can change but is not usualy?. I Know conclusive will be at 12 weeks after exposure.
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Avatar universal
Post-test discussion

The need for a repeat HIV test if still within the window period after a specific exposure should be discussed. Although fourth generation tests shorten the time from exposure to seroconversion a repeat test at three months is still recommended to definitively exclude HIV infection.

http://www.bhiva.org/documents/Guidelines/Testing/GlinesHIVTest08.pdf
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Avatar universal
http://www.fda.gov/downloads/BiologicsBloodVaccines/BloodBloodProducts/ApprovedProducts/LicensedProductsBLAs/BloodDonorScreening/InfectiousDisease/UCM216314.pdf

Page 27
Current methods for the detection of HIV may not detect all infected individuals. An ARCHITECT HIV Ag/Ab Combo test result that is nonreactive does not exclude the possibility of exposure to or infection with HIV-1 and/or HIV-2. Nonreactive results in this assay for individuals with prior exposure to HIV-1 and/or HIV-2 may be due to antigen and antibody levels below the limit of detection of this assay.

3 months is conclusive.
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Avatar universal
There are no tests marketed or sold that will give a conclusive negative test result earlier that 3 months. Duo test can detect HIV one week earlier than a 3rd generation test but it does not change the time as when to obtain a conclusive negative test result.
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Avatar universal
by Emily_MHModerator , May 06, 2010 07:28AM


On MedHelp, we follow the guidelines set by the Centers for Disease Control (CDC), test manufacturers, FDA, and our experts, Drs. HHH and Hook.

For this forum, it is 3 months. Yes, a 6 or 8 week test may be accurate, but it's not conclusive until 3 months. Saying that the 6 or 8 week test is a good indicator is fine, but to be conclusive, testing must happen at 3 months. It is also this forum's position that oral sex by itself does not require testing.

You can quote doctors, but make sure you say that. Doctors are licensed to practice medicine and can say that given the particulars about exposure, timing, etc., that someone doesn't need more testing. However, unless you are a doctor, you can't say that.

Emily
MedHelp
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Avatar universal
I have read several times on the expert forum of this site that a test at four weeks will detect over 90 percent of exposures and at 8 weeks they will detect near 99 percent of exposures. Furthermore you had a single act which is not very likely to transmit the virus and you do not know whether your partner had hiv,which it is unlikely he did as most gay men do not. Get tested again by three months but i can tell you that the doctors on this site say that a test at 8 weeks is nearly conclusive and it is very rare for hiv not to be detected at this point because the overwhelming majority of people would have suroconverted and thus the virsus would be picked up at this time.

Just by doing a brief scan this is what i saw posted by dr. hook and one by dr handsfield. The dates are listed with them, so again if you want you can get tested at three months but it is virtually a certainty that you dont have hiv!

Edward W Hook, MD, Jul 03, 2010 11:11AM
3. No, not from a medical perspective.  If you need to do so for your own peace of mind, a single HIV antibody test at 6-8 weeks should provide confirmation that you did not get HIV from the activities you describe.

by H. Hunter Handsfield, M.D., May 17, 2010 01:52PM  

2) Mostly we agree with Teak's advice on the community forum.  However, he is mistaken about the Duo test, i.e. combined test for HIV antibody and p24 antigen.  A negative Duo test at 28 days is virtually 100% proof against a new HIV infection.  Your test result proves you weren't infected.
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Avatar universal
3 months post exposure will be when you can obtain your conclusive test result.
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Avatar universal
is that possible?

are you talking about the doctor from this website or which website? iI tried to find it but i couldn´t.

many thanks for your time
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Avatar universal
The doctors on the expert forum of this site state that 8 weeks is nearly conclusive like around 99 percent or more and that those who it wouldn't detect would likely have a serious illness like cancer or etc. Furthermore your one time exposure is said to put you at like a one percent per act risk according to the experts as well. When you combine that with the fact that most gay men do not have hiv, your likelihood of being positive is incredibly miniscule. Obviously you know you made a mistake but if you just combined your odds of one percent at best for the test being wrong, combined with one percent per act risk, then comnbined with the fact most even gay men do not have hiv it is very very unlikely that you have hiv. The doctors on medhelp always advise you first ask your partner their status before ever engaging in even protected sex, and obviously use protection for all anal or vaginal sex. None the less your likelihood of having hiv is nearly 0!
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