Aa
Eye turning yellow and yellow skin.
My Mum Started the tripple therapy on 12th May. i noticed today that her eyes are yellow and also her skin in yellow.
Is it serious, what need to be done in such situations. She is feeling very week. Any suggestions what we can do to ease the disconfort and weekness.
Is it serious, what need to be done in such situations. She is feeling very week. Any suggestions what we can do to ease the disconfort and weekness.
Hi I see your Mum is 1A. I have copied this message from Hector. I hope he doesn't mind. I believe this would be what your Mom would take after recovering
"The European regulator in January approved Sovaldi (sofosbuvir) for use both in combination with pegylated interferon alpha and ribavirin in patients with hepatitis C If this is the treatment your mother doctor will be using this is the correct treatment for her. Or some combination of this drug with others.
The most common adverse events (≥ 20%) for SOVALDI + peginterferon alfa + ribavirin combination therapy were fatigue, headache, nausea, insomnia and anemia. While many people experience some side effects on this treatment very few every have to stop treatment because of them.
The first-generation protease inhibitors telaprevir (Incivek or Incivo) or boceprevir (Victrelis) that the others are mentioning should NOT be used for treatment of genotype 1 HCV infection in the EU.
The European Association for the Study of the Liver (EASL) has issued new guidelines for the treatment of hepatitis C, which recommend that wherever possible, patients should be treated with the newest direct-acting antivirals. The guidelines also recommend physicians should "mix and match" antivirals from different companies to get the most potent regimens.
Good luck to your mother.
Hector"
I looked up info, it looks as if your Mum would take the Sovaldi, Riba, Peg, for 12 weeks. Each tx is individualized so I am not positive. I saw a person on here who could not take the peg so had to do Sovaldi and Riba for 24 weeks. Her doctor would decide. I am glad to hear the doctor called. When I treated there was an emergency number I could call though I preferred to talk to his nurse as she was much easier to talk to and seemed more knowledgeable :)
"The European regulator in January approved Sovaldi (sofosbuvir) for use both in combination with pegylated interferon alpha and ribavirin in patients with hepatitis C If this is the treatment your mother doctor will be using this is the correct treatment for her. Or some combination of this drug with others.
The most common adverse events (≥ 20%) for SOVALDI + peginterferon alfa + ribavirin combination therapy were fatigue, headache, nausea, insomnia and anemia. While many people experience some side effects on this treatment very few every have to stop treatment because of them.
The first-generation protease inhibitors telaprevir (Incivek or Incivo) or boceprevir (Victrelis) that the others are mentioning should NOT be used for treatment of genotype 1 HCV infection in the EU.
The European Association for the Study of the Liver (EASL) has issued new guidelines for the treatment of hepatitis C, which recommend that wherever possible, patients should be treated with the newest direct-acting antivirals. The guidelines also recommend physicians should "mix and match" antivirals from different companies to get the most potent regimens.
Good luck to your mother.
Hector"
I looked up info, it looks as if your Mum would take the Sovaldi, Riba, Peg, for 12 weeks. Each tx is individualized so I am not positive. I saw a person on here who could not take the peg so had to do Sovaldi and Riba for 24 weeks. Her doctor would decide. I am glad to hear the doctor called. When I treated there was an emergency number I could call though I preferred to talk to his nurse as she was much easier to talk to and seemed more knowledgeable :)
My Hepatologist told me once he had several people became jaundice whilst on treatment with telaprevir.
some had to stop other could continue as the
jaundice disappeared again, but they were under very strict surveillance.
some had to stop other could continue as the
jaundice disappeared again, but they were under very strict surveillance.
Hi Olga, sorry I did not see where you were from. I panicked when I saw your Mum was yellow. I have never heard of anyone turning yellow while on tx. Yes, she will be weak and tired. Did they tell you what her hemoglobin was? If that has dropped it will make her very tired. Mine was 14.8 dropped to 9.7. I could barely walk. My legs were very weak and in fact if I stood for too long my feet and ankles would go numb. When the hemoglobin gets low our body is not getting enough oxygen When I did I would get very out of breath and it would take a long time to recover, hours.
When I called the doctor they told me to lay down. I am very glad to hear that your doctor is aware of what is happening. I am so sorry for what you both experienced. If you are able please try to keep copies of your Mum's blood work. It can be very helpful.
I think her doctor had mentioned that she had to try this first. So...I would imagine that once your Mum recovers she will put her on new meds. They are not as hard on the body, don't have the harsh side effects and are a much shorter treatment. It depends what Geno type she is. You may have said, I will go look.
Thank you so much for keeping in touch. I bet you are exhausted. Take care of yourself.
My best
Dee
When I called the doctor they told me to lay down. I am very glad to hear that your doctor is aware of what is happening. I am so sorry for what you both experienced. If you are able please try to keep copies of your Mum's blood work. It can be very helpful.
I think her doctor had mentioned that she had to try this first. So...I would imagine that once your Mum recovers she will put her on new meds. They are not as hard on the body, don't have the harsh side effects and are a much shorter treatment. It depends what Geno type she is. You may have said, I will go look.
Thank you so much for keeping in touch. I bet you are exhausted. Take care of yourself.
My best
Dee
Thank you very much Dee for your support.. We went to the emergency room, but our doctor contact us as soon as she saw missed calls, so she was in contact with the medical staff in emergency room and she made the desigion to stop treatment. i am worry abot high bilirubin, but doctor told me do nothing about , just get fresh air, drink max 2 littre of fluid and eat as normal... But my mum soo tired, her legs are too weak and next appoitment is on Wednesday... is it right?
yes, from London..
yes, from London..
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Please have her drink a lot of water to help flush the medication out of her system. As I had said before I found that this was a severe reaction, it was listed in the site that I had sent you.
I am not a doctor however I would think that she will need to recover from this first before they do anything.
Then perhaps she can be put on one of the newer medications. You had mentioned that her doctor said she had to try this first.
She should now be eligible for the newer meds. There is a lot of financial help out there if she doesn't have insurance. Even if she had insurance there is still financial help.
I am sure others will be a long to help and I will search for it as well. Please let us know how your Mum is doing and what her doctor says, if her doctor is not a hepatologist, please find her one. She will need close supervision during her next tx by a liver specialist. Where do you live? Perhaps we can help you find one in your area.
Take care, thank God you were there for her
My best
De