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Eye turning yellow and yellow skin.
My Mum Started the tripple therapy on 12th May. i noticed today that her eyes are yellow and also her skin in yellow.
Is it serious, what need to be done in such situations. She is feeling very week. Any suggestions what we can do to ease the disconfort and weekness.
Is it serious, what need to be done in such situations. She is feeling very week. Any suggestions what we can do to ease the disconfort and weekness.
Thank you very much guys for your help, trying to call our doctor, but she is not answering...
Acute jaundice is a medical emergency.
She needs to have immediate medical care.
Contact a doctor ASAP or take her to a hospital.
Jaundice is a sign of severe liver dysfunction. Treatment with peg-interferon and ribavirin can cause liver decompensation or liver failure in certain individuals with advanced liver disease. Here in the US, people with cirrhosis of the liver are advised not to use this treatment because of the risks of serious medical issues caused by this treatment.
The American Association for the Study of Liver Diseases (AASLD) and Infectious Diseases Society of America (IDSA) say...
"Although regimens of PEG/RBV plus telaprevir (Incivek) or boceprevir for 24 to 48 weeks using RGT are also FDA approved, they are markedly inferior to the preferred and alternative regimens.
These regimens are associated with their higher rates of serious adverse events (eg, anemia and rash), longer treatment duration, high pill burden, numerous drug-drug interactions, frequency of dosing, intensity of monitoring for continuation and stopping of therapy, and the requirement to be taken with food or with high-fat meals."
Cheers!
Hector
She needs to have immediate medical care.
Contact a doctor ASAP or take her to a hospital.
Jaundice is a sign of severe liver dysfunction. Treatment with peg-interferon and ribavirin can cause liver decompensation or liver failure in certain individuals with advanced liver disease. Here in the US, people with cirrhosis of the liver are advised not to use this treatment because of the risks of serious medical issues caused by this treatment.
The American Association for the Study of Liver Diseases (AASLD) and Infectious Diseases Society of America (IDSA) say...
"Although regimens of PEG/RBV plus telaprevir (Incivek) or boceprevir for 24 to 48 weeks using RGT are also FDA approved, they are markedly inferior to the preferred and alternative regimens.
These regimens are associated with their higher rates of serious adverse events (eg, anemia and rash), longer treatment duration, high pill burden, numerous drug-drug interactions, frequency of dosing, intensity of monitoring for continuation and stopping of therapy, and the requirement to be taken with food or with high-fat meals."
Cheers!
Hector
Hi again Olga,
I read your first post, and I see now that your Mum is on triple therapy with Incivek, Ribavirin, and Interferon. Jaundice is not a normal side effect of this therapy, and as Dee said can be a serious condition. This is a difficult treatment and can be very hard on someone whose liver is already not working well. If your Mum has Cirrhosis, and she is taking triple therapy with Incivek, and she is jaundiced, I think it is best to call her doctor's office and find out what to do.
Please make sure she doesn't take any Tylenol, have her drink a lot of fluids, and find out from her doctor's office what to do next.
Advocate1955
I read your first post, and I see now that your Mum is on triple therapy with Incivek, Ribavirin, and Interferon. Jaundice is not a normal side effect of this therapy, and as Dee said can be a serious condition. This is a difficult treatment and can be very hard on someone whose liver is already not working well. If your Mum has Cirrhosis, and she is taking triple therapy with Incivek, and she is jaundiced, I think it is best to call her doctor's office and find out what to do.
Please make sure she doesn't take any Tylenol, have her drink a lot of fluids, and find out from her doctor's office what to do next.
Advocate1955
Hi Olga,
Can you tell us more about the triple therapy that your Mum is on? Can you tell us the names of the three medications?
In any case, yellow skin and yellow eyes is a sign of jaundice, Jaundice is a condition in which there is too much bilirubin and a sign that your Mum's liver is not able to perform all of it's tasks.
Jaundice can be a sign of a serious problem. It could be an indicator that her liver is beginning to fail, it could be a sign that she has a gall bladder problem or a problem with her pancreas. Or it could be an adverse reaction to her treatment medications. Is it possible that she may have taken acetaminophen? Acetaminophen can also damage the liver, especially in someone whose liver is already compromised.
Other symptoms to watch for may include dark urine or pale stools.
As Dee said, please contact your Mum's doctor's office and find out what to do in an emergency today.
Again, please let us know which three medications your Mum is taking, and perhaps we can find more information.
Advocate1955
Can you tell us more about the triple therapy that your Mum is on? Can you tell us the names of the three medications?
In any case, yellow skin and yellow eyes is a sign of jaundice, Jaundice is a condition in which there is too much bilirubin and a sign that your Mum's liver is not able to perform all of it's tasks.
Jaundice can be a sign of a serious problem. It could be an indicator that her liver is beginning to fail, it could be a sign that she has a gall bladder problem or a problem with her pancreas. Or it could be an adverse reaction to her treatment medications. Is it possible that she may have taken acetaminophen? Acetaminophen can also damage the liver, especially in someone whose liver is already compromised.
Other symptoms to watch for may include dark urine or pale stools.
As Dee said, please contact your Mum's doctor's office and find out what to do in an emergency today.
Again, please let us know which three medications your Mum is taking, and perhaps we can find more information.
Advocate1955
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Please have her drink a lot of water to help flush the medication out of her system. As I had said before I found that this was a severe reaction, it was listed in the site that I had sent you.
I am not a doctor however I would think that she will need to recover from this first before they do anything.
Then perhaps she can be put on one of the newer medications. You had mentioned that her doctor said she had to try this first.
She should now be eligible for the newer meds. There is a lot of financial help out there if she doesn't have insurance. Even if she had insurance there is still financial help.
I am sure others will be a long to help and I will search for it as well. Please let us know how your Mum is doing and what her doctor says, if her doctor is not a hepatologist, please find her one. She will need close supervision during her next tx by a liver specialist. Where do you live? Perhaps we can help you find one in your area.
Take care, thank God you were there for her
My best
De