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Thrush and ureaplasma

I have had a problem with vaginal thrush since my early twenties (usually following antibiotic courses) but nearly 12 months ago (I am 41) started getting thrush every month around ovulation time. It has been confirmed by my gynae on 3 cultures and sensitivity tests since last April, and I need to take 3 doses of Diflucan 150mg 3 days apart to clear each episode. I am not convinced the discharge goes away completely each time although it is less and the symptoms of inflammation and itching are absent. Ultrasound scans of the uterus appear normal and pap smears normal. No bacteria have been found before but Ureaplasma was cultured 2 weeks ago and he has prescribed Erithromycin 500mg qid  for 7 days (a dose I understand to be very high and will undoubtedly spark off my thrush!). I have had blood tests last week: all within normal limits (blood glucose (fasting); full blood count; and autoimmune profile and I have no other health problems. My husband is circumcised and we have always used condoms.

My question is: could Ureaplasma be responsible for my recurrent thrush problem or is it likely to be an insignificant secondary opportunist in this situation? I understand it is a sexually transmitted disease so if I take the erithromycin, shouldn't my husband be treated as well? I find it strange that it has not been cultured before and is being held responsible for my thrush.
Best Answer
1415174 tn?1453243103
HI KV1970,
sorry about your problem. Firstly, have you ever been actually cutured or had a smear taken to prove you have yeast and not just Ureaplasma? Sometimes Ureaplasma can feel like thrush. Erythromycin used to be the standard drug of treatment for ureaplasma urealyticum but because it has become resistant to Erythromycin the drug of choice is doxycycline.  The doctor may be trying Erythro on you because of the yeast problem but it may or may not work. So, if it doesn't work you know why. Also, since your husband uses a condom you don't necessarily have to have him be treated but you could possibly get it from him so it would be better for both of you to be treated as least that is what I would do since you are having so many problems. Yeast can be acquired from the hands so I would be very careful for both of you to wash you hands well before having any kind of genital forplay and sex. It can also just be cross contaminated from the anal area. Since it has started  up near your ovulation time I would bring this up with the doctor again. Ureaplasma is normal genital flora (bacteria) in sexually active persons. It can be an STD since it is acquired that way. I haven't seen any reports yet that state that yeast causes Ureaplasma or vice versa. Yeast is very common and easy to get.  I hope this helps. Let me know if you have any questions.
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Avatar universal
I am sorry but I don't know enough about it to really comment and I am the only one on these boards right now. So my advice is to follow up with your Dr.
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