This forum is for questions and support regarding ovarian cancer issues, such as: Biopsy, Chemotherapy, Clinical Trials, Genetics, Hysterectomy, Immunotherapy, Ovarian Cancer Types, Radiation Therapy, Risk Factors, Screening, Staging, Surgery.
I was dx May 06 stage 3c. Did 4 rds cisplatin/taxol i.p.. then 4 rds carbo/taxol i.v.. Finished Jan.07. Ca125 started rising slowly in Aug.07. ptct in Sept clear. Oct. 19 appt. found intestinal (small int) blockage had same day surgery. Onc/gyn did not see cancer, blockage was adhesion twisting intestine. Pathology slides and fliud positive for ca. Started Gemzar/carbo day 1, with gemzar day 8. First rd, could not do day 8 until day 14 because of red blood and platelets. Rd. 2 could not do day 8 until day 21 same reason ( had aranesp shots) Rd 3 carbo reaction they said, although it didn't happen until i finished the carbo and gemzar drip. How do they know was it? Could not do day 14 of Gemzar again thursday for platelets. come back next thursday. Had ct this past thursday, clear. Dr. said she was adding cytoxan on rd. 4. I never heard of this combo, Looked it up and now I am worried that it will make platelets and red blood even worse. Platelets were 71 on valentines> What do you make of this? I am really worried. I stay so tired and weak i don t go anywhere except chemo. I go to west clinic in memphis, 110 miles drive.I take neupogen (3) at home for white blood.My ca125 is now 28. (was 265 oct.) Is my dr. aggressive by not just using gemzar?Thanks
Hi Ms Jazz,
thank you for your complete information. I have had the same experience with many of my patients when they are taking gemzar/ carbo. I think the gemzar is very hard on the platelets.
I am not familiar with the combination of adding cytoxan to the mix. Cytoxan is definitely a great drug and has been used in many combinations - most famously : cisplatin/cytoxan (CP), or cisplatin, adriamycin, cytoxan (CAP). Most recently oral cytoxan given daily at 50 mg a day is well tolerated.
I think you need to sit down with your good doctor and go over your appropriate concerns about bone marrow toxicity. It may be reasonable to just give carboplatin by itself, cytoxan alone, or even gemzar alone. Another option is stop now and watch closely.
Please let us know what you decide
Copyright 1994-2016 MedHelp International. All rights reserved.
MedHelp is a division of Aptus Health.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.