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Respiratory Disorders  (Expert Forum)
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Spirometry Results and Yearly Changes
Answered by
David Tinkelman, M.D. - Respiratory Disorder
National Jewish Health CO
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Spirometry Results and Yearly Changes

by vancouverasking, Oct 02, 2009 04:26PM
Hello;
I am hoping that you may able to provide some information/interpretation regarding relatively normal spirometry results and lower than normal FEF 25-75% results.  I am a 47 years old, smoked for 12 pack years, and quit smoking 15 years ago.  There was a slight (6%) increase after the broncial challenge test. I had a very slight cold/allergy when completing the test. Last year when it was completed by FEV1/FVC was 98% and FEF25-75% was 82% ( at a different lab). Also,would there be an explanation for this decline within 1 year? My Mother and Uncle both have COPD which was diagnosed in their late 60's.
  
FVC - 115%
FEV1 - 98%
FEV1/FVC - 84% (will this decrease over time?)
FEF25-75% - 56%
PEF - 125

Lung Volumes
VC - 120%
TLC - 110%
FRC PL - 103%
RV - 97%
RV/TLC -30

Diffusion
DLCO - 95%
DLCO/VA - 85%

I am very concerned. Thanks in advance.

Michele

by David Tinkelman, M.D., Oct 05, 2009 04:52PM
To: vancouverasking
The FEV1/FVC ratio slowly decreases with aging and 84% is probably within normal limits.  The difference, 84% vs 98% could be on the basis of different laboratories.  Your current spirometric values are, with the exceptions of the FEF25-75% and the PEF, are WNL and that includes your lung volues, the RV/TLC and the diffusing capacity.  That the FEF25-75% and PEF are reduced in the presence of a normal FEV1 suggests that the reduced values are a reflection of less than optimum effort.  Given your other normal values, I would place very little significance on the FEF25-75% (historically deemed by some to be a sign of small airway disease).  These findings do not suggest, even early, COPD.  You should request a copy of the PFT interpretation but, in the meantime, you have no reason to be concerned about your lungs.

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