You wife may have these symptoms due to the severe coronary artery disease and with a reasonably good left ventricle these symptoms should improve with medical management.
The fact that she did not have heart damage with the closure of the circumflex may mean that there are microscopic collaterals that are keeping this part of the heart alive. They may to small to be seen with the angiogram. The best way to ensure both the vein grafts and the internal mammary is medical management with control of the diabetes and aggressive statin therapy.