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Interventional Cardiology  (Expert Forum)
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Increase in resting heart rate related to Norvasc?
Answered by
Truman Medical Center MO
Questions in the Interventional Cardiology forum are answered by medical professionals affiliated with the Truman Medical Center. Topics covered include acute coronary syndrome, angina , atrial fibrillation , cardiac catheterization , cardiomyopathy , drug abuse & cardiac disease, echocardiography , heart failure , hypertension & heart disease , lipid management , minorities and heart disease, peripheral vascular disease prevention, valvular heart disease , women’s heart health, and the warning signs of a heart attack.

Increase in resting heart rate related to Norvasc?

by sarrae, Nov 18, 2008 06:35PM
After 2 years of angina, I was diagnosed in 6/08 with coronary vasospasms/Prinzmetal's angina (suspected diagnosis, no angio w/ergonovine). Anxiety, GERD, mitrovalve prolapse ruled out. Have had thallium stress test, several stress echoes, exercise treadmill, several EKG's all normal. Holter has shown some PVC's but nothing of note.

I was given Amlodipine and gradually increased to 20 mg/day which has decreased my angina attacks to a couple of times a month, a remarkable improvement. For the past few months (probably since the increase to 10mg) I have noticed my resting heart rate has gone from 69-73 bpm to the high 90's. When I am doing simple things like cooking, it raises to 110-115. My BP is now well into a normal range (diagnosed with hypertension several years ago) but the heart rate is higher. I was hospitalized about a month ago when my resting rate was 132 and discharged when it gradually went back to 105 with no explanation. My potassium is low at times but I have been taking a prescribed potassium supplement daily with no change to heart rate. Any advice would be helpful.
30 yr female, no children
non-smoker, moderate drinker
meds: 20 mg Amlodipine
          birth control pill
          potassium supplement
          81 mg aspirin

Thank you,
S. Rosser

by Douglas Bogart, MD, Nov 18, 2008 07:39PM
To: sarrae
Norvasc is a vasodilator and as such can cause a reflex tachycardia.  There are other drugs which might be as effective for your problem--like diltiazem--that will not cause the tachycardia.
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