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Ive been on synthroid for 10 years and have had no problems. I've been on the border several times and it has always worked itself out. I developed PVC's recently and went to the emergencyEmergency airway puncture Emergency contraception room to find out my TSHPituitary and tsh Tsh was 0.03. They took me off synthroid for 3 days and started me backup with 88mg from 100. I developed heart fluttersAtrial fibrillation/flutter again within 4 days. Should I stay off the meds for a week or two before I start up again. I know this will throw me back into Hypo. What can cause the sudden change.