I am sorry, but there is no cure for systemic mastocytosis. The treatment is mainly supportive and aimed at keeping the symptoms under control. Patients are asked to keep epinephrine injections or Epipen handy and taught to use it in emergency. Various chemotherapy or drugs are tried with variable response depending on symptoms. You cannot take beta blocker drugs. Also you need to be closely monitored before any tests and injections and procedures. Presence of anemia, leukopenia or low white blood cells and/or low platelets or thrombocytopenia, and or elevated lactate dehydrogenase worsens prognosis. Take care!